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Streams are regional resources. If your application knows which region owns a stream, you can include a region header to avoid an extra redirect/retry step. Clients may send:
or:
If a request reaches the wrong region, the API returns 409 with a region_error body that identifies the expected or requested region. Responses expose X-Overshoot-Region with the serving region.
One chat-completions request cannot reference streams from multiple regions.